Add to ORKGAntifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifungal resistant pathogens have increased during the past decade, becoming a serious concern. Candida albicans has been the most extensively studied pathogen in antifungal resistance because of their morbidity and mortality associated with infections in immunocompromised patients. This review describes the antifungal mechanims of the azole fluconazole widely used for the prophylaxis and treatment of candidal infections. The specific molecular pathways occurring in fluconazole-resistance of C. albicans and some issues about new antifungal agents are also discussed
Candida albicans is the most prevalent cause of fungemia worldwide. Its ability to develop resistanc...
Azole resistance in Candida albicans can be mediated by several resistance mechanisms. Among these, ...
Widespread and repeated use of fluconazole in the prophylaxis and therapy resulted in resistance amo...
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifu...
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifu...
The use of antifungal agents, especially the azole class, has increased in parallel with a higher in...
Candida albicans and the emerging non-albicans Candida spp. have significant clinical relevance amon...
Failures of drug treatment in fungal infections combined with improvements in performances and stand...
Molecular mechanisms of azole resistance in Candida albicans, including alterations in the target en...
Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal ca...
Mechanisms of antifungal resistance of azoles in Candida albicans. A review Candida albicans is a co...
The epidemiology of Candida infections has changed in recent years. Although Candida albicans is sti...
Fluconazole-resistant Candida albicans, a cause of recurrent oropharyngeal candidiasis in patients w...
A limited number of antifungal agents including azoles, polyenes, pyrimidine analogues are used toda...
A limited number of antifungal agents including azoles, polyenes, pyrimidine analogues are used toda...
Candida albicans is the most prevalent cause of fungemia worldwide. Its ability to develop resistanc...
Azole resistance in Candida albicans can be mediated by several resistance mechanisms. Among these, ...
Widespread and repeated use of fluconazole in the prophylaxis and therapy resulted in resistance amo...
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifu...
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifu...
The use of antifungal agents, especially the azole class, has increased in parallel with a higher in...
Candida albicans and the emerging non-albicans Candida spp. have significant clinical relevance amon...
Failures of drug treatment in fungal infections combined with improvements in performances and stand...
Molecular mechanisms of azole resistance in Candida albicans, including alterations in the target en...
Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal ca...
Mechanisms of antifungal resistance of azoles in Candida albicans. A review Candida albicans is a co...
The epidemiology of Candida infections has changed in recent years. Although Candida albicans is sti...
Fluconazole-resistant Candida albicans, a cause of recurrent oropharyngeal candidiasis in patients w...
A limited number of antifungal agents including azoles, polyenes, pyrimidine analogues are used toda...
A limited number of antifungal agents including azoles, polyenes, pyrimidine analogues are used toda...
Candida albicans is the most prevalent cause of fungemia worldwide. Its ability to develop resistanc...
Azole resistance in Candida albicans can be mediated by several resistance mechanisms. Among these, ...
Widespread and repeated use of fluconazole in the prophylaxis and therapy resulted in resistance amo...