Objective: The lipid profile of synovial fluid (SF) is related to the health status of joints. The early stages of human osteoarthritis (OA) are poorly understood, which larger animals are expected to be able to model closely. This study examined whether the canine groove model of OA represents early OA in humans based on the changes in the lipid species profile in SF. Furthermore, the SF lipidomes of humans and dogs were compared to determine how closely canine lipid species profiles reflect the human lipidome. Methods: Lipids were extracted from cell-and cellular debris-free knee SF from nine donors with healthy joints, 17 patients with early and 13 patients with late osteoarthritic changes, and nine dogs with knee OA and healthy contrala...
Abstract Anomalies of fatty acid (FA) metabolism characterize osteoarthritis (OA) and rheumatoid ar...
Osteoarthritis (OA) is a complex, multifactorial, and slowly progressive disease where there is curr...
Abstract Cardiovascular diseases are often associated with impaired lipid metabolism. Animal models ...
Objective: The lipid profile of synovial fluid (SF) is related to the health status of joints. The e...
<div><p>Articular synovial fluid (SF) is a complex mixture of components that regulate nutrition, co...
Secondary osteoarthritis (OA) is a slow progressive, common disorder of synovial joints in dogs. It ...
<p>Lipids were determined by electrospray ionization tandem mass spectrometry (ESI-MS/MS) or liquid ...
International audienceLipids, especially lysophosphatidylcholine LPC16:0, have been shown to be invo...
[Abstract] Objective: Synovial inflammation is one of the most characteristic events in different ty...
Articular synovial fluid (SF) is a complex mixture of components that regulate nutrition, communicat...
Glycosaminoglycans are natural components of healthy joint cartilage and they also appear in healthy...
Secondary, non-inflammatory osteoarthritis (OA) is a common disorder in dogs. Its silent onset preve...
© 2020, The Author(s). Introduction: Osteoarthritis (OA) is the most common form of joint disease, c...
Objective: The aim of this study was to carry out a targeted phospholipidomic analysis on synovial f...
Synovial fluid (SF) has unique properties regarding the maintenance of joint homeostasis. It consis...
Abstract Anomalies of fatty acid (FA) metabolism characterize osteoarthritis (OA) and rheumatoid ar...
Osteoarthritis (OA) is a complex, multifactorial, and slowly progressive disease where there is curr...
Abstract Cardiovascular diseases are often associated with impaired lipid metabolism. Animal models ...
Objective: The lipid profile of synovial fluid (SF) is related to the health status of joints. The e...
<div><p>Articular synovial fluid (SF) is a complex mixture of components that regulate nutrition, co...
Secondary osteoarthritis (OA) is a slow progressive, common disorder of synovial joints in dogs. It ...
<p>Lipids were determined by electrospray ionization tandem mass spectrometry (ESI-MS/MS) or liquid ...
International audienceLipids, especially lysophosphatidylcholine LPC16:0, have been shown to be invo...
[Abstract] Objective: Synovial inflammation is one of the most characteristic events in different ty...
Articular synovial fluid (SF) is a complex mixture of components that regulate nutrition, communicat...
Glycosaminoglycans are natural components of healthy joint cartilage and they also appear in healthy...
Secondary, non-inflammatory osteoarthritis (OA) is a common disorder in dogs. Its silent onset preve...
© 2020, The Author(s). Introduction: Osteoarthritis (OA) is the most common form of joint disease, c...
Objective: The aim of this study was to carry out a targeted phospholipidomic analysis on synovial f...
Synovial fluid (SF) has unique properties regarding the maintenance of joint homeostasis. It consis...
Abstract Anomalies of fatty acid (FA) metabolism characterize osteoarthritis (OA) and rheumatoid ar...
Osteoarthritis (OA) is a complex, multifactorial, and slowly progressive disease where there is curr...
Abstract Cardiovascular diseases are often associated with impaired lipid metabolism. Animal models ...