Treatment of white coat HYpertension in the very elderly trial (HYVET 2) - Feasibility of a randomized controlled trial (study protocol)
- Okorie, Michael
- Ali, Khalid
- Bremner, Stephen
- Beckett, Nigel
- Jackson, Stephen
- Quirk, Richard
- McAlister, Colin
- Perry, Nicky
- Potter, John
- Bulpitt, Christopher
- Rajkumar, Chakravarthi
DOIAbstract
The results of HYpertension in the Very Elderly Trial (HYVET) were crucial in providing evidence of benefit of the treatment of hypertension in those 80 years or older. Following a subsequent sub study analysis of the HYVET data there is a suggestion that 50% of patients in the main study had White Coat Hypertension (WCH), defined as clinic BP readings >140/90 mmHg and ambulatory BP readings <135/85 mmHg. Currently, definitive evidence in support of treatment for such individuals is not available. HYVET 2 has been designed in order to assess the feasibility of conducting a randomized controlled trial which might determine whether the treatment of WCH in the very elderly is clinically beneficial. One hundred participants aged ≥75 years diagn...
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