The establishment of a complex collagen network is critical for the architecture and mechanical properties of cartilage and bone. However, when and how the key collagens in cartilage and bone develop has not been characterised in detail. The study provides a detailed qualitative characterisation of the spatial localisations of collagens I-III, V-VI and IX-XI in the mouse and their regional architecture variation over three developmentally significant time points: when the rudiment starts to form at E13.5 [Theiler stage (TS) 22], when mineralisation is present at E16.5 (TS25) and during the latest prenatal stage at E18.5 (TS27). Dynamic changes in collagen distribution between stages with the progression of the growth plate and mineralisatio...
Collagen, the most abundant protein in the body, can be found throughout in a variety of places incl...
Articular cartilage is a remarkable tissue with mechanical performance that surpasses engineering st...
Collagen II is a fibril-forming collagen that is mainly expressed in cartilage. Collagen II-deficien...
AbstractObjective The STR/ort mouse develops a naturally occurring osteoarthritis of the femorotibia...
SummaryObjectiveThe structure and composition of articular cartilage change during development and g...
AbstractObjective: To determine in articular cartilage whether degraded type II collagen is more abu...
SummaryObjectivesThe present study was designed to reveal changes in the collagen network architectu...
Collagen type XI is a quantitatively minor yet essential component of the collagen fibrils within ca...
AbstractMice that are homozygous for the autosomal recessive chondrodysplasia (cho) mutation die at ...
BACKGROUND:Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the ...
Skeletogenesis occurs through both intramembranous ossification, and endochondral ossification, the ...
During the skeletal development cartilage composition changes as cartilage maturation proceeds [1]. ...
Mice that are homozygous for the autosomal recessive chondrodysplasia (cho) mutation die at birth wi...
Summary: Objective: We aimed to directly quantify the zone-specific evolution in morphology of coll...
Collagen is a vital material in the tissues of living organisms. Found almost everywhere in the huma...
Collagen, the most abundant protein in the body, can be found throughout in a variety of places incl...
Articular cartilage is a remarkable tissue with mechanical performance that surpasses engineering st...
Collagen II is a fibril-forming collagen that is mainly expressed in cartilage. Collagen II-deficien...
AbstractObjective The STR/ort mouse develops a naturally occurring osteoarthritis of the femorotibia...
SummaryObjectiveThe structure and composition of articular cartilage change during development and g...
AbstractObjective: To determine in articular cartilage whether degraded type II collagen is more abu...
SummaryObjectivesThe present study was designed to reveal changes in the collagen network architectu...
Collagen type XI is a quantitatively minor yet essential component of the collagen fibrils within ca...
AbstractMice that are homozygous for the autosomal recessive chondrodysplasia (cho) mutation die at ...
BACKGROUND:Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the ...
Skeletogenesis occurs through both intramembranous ossification, and endochondral ossification, the ...
During the skeletal development cartilage composition changes as cartilage maturation proceeds [1]. ...
Mice that are homozygous for the autosomal recessive chondrodysplasia (cho) mutation die at birth wi...
Summary: Objective: We aimed to directly quantify the zone-specific evolution in morphology of coll...
Collagen is a vital material in the tissues of living organisms. Found almost everywhere in the huma...
Collagen, the most abundant protein in the body, can be found throughout in a variety of places incl...
Articular cartilage is a remarkable tissue with mechanical performance that surpasses engineering st...
Collagen II is a fibril-forming collagen that is mainly expressed in cartilage. Collagen II-deficien...