High-performance production of monodisperse emulsions using microfabricated asymmetric through-hole array

This paper reports high-performance production of monodisperse emulsions using numerous asymmetric through holes microfabricated on a silicon chip. Monodisperse oil-in-water (O/W) emulsions with droplet sizes of approximately 30 µm were stably produced via asymmetric through holes at high droplet generation rates up to several hundreds of thousands per second. This paper also reports three-dimensional simulation of emulsion droplet generation via an asymmetric through hole using a computational fluid dynamics (CFD) method. The calculation results showed an excellent agreement with the experimental results and provided a better understanding of the droplet generation process