A new approach for the preparation of functional pharmaceutical nanoparticles using glass capillary millifludic devices

Functional pharmaceuticals nanoparticles are solid carriers with a mean size of less than 1 μm, which are capable to dissolve, entrap, encapsulate or attach active ingredients (drug) to its nanoparticle matrix. In this study, a new approach for the formation of acetaminophen (PCM) encapsulated poly(ɛ-caprolactone) (PCL) nanoparticles with controllable size dependent has been performed in a glass capillary milifluidic device by nanoprecipitation (“diffusion-stranding”) method