Physiological responses to concurrent resistance exercise and high-intensity interval training: implications for muscle hypertrophy

It is recommended that individuals perform a combination of resistance exercise RE) and endurance exercise. Lack of time is often cited as a reason for being unable to meet current exercise guidelines. Therefore, combining both forms in one session may be beneficial. However, research continues to elucidate whether interference of adaptive outcomes occurs when RE and endurance exercise are performed concurrently. A proposed interference effect suggests that concurrent training may dampen RE-induced adaptations (e.g., muscle strength and growth) compared to retraining only. This thesis has further investigated this issue by examining the molecular, functional and muscular adaptations to acute and chronic concurrent RE and high-intensity interval training (HIIT) compared to RE only in both healthy individuals and individuals at risk of or with type 2 diabetes mellitus (T2DM). [Continues.