Retention studies in supercritical fluid chromatography

There has been considerable interest in the field of Supercritical Fluid Chromatography (SFC) and it is fast becoming recognised as a very useful analytical tool, offering the speed of separation found with gas chromatography (GC) with the solvating power of high performance liquid chromatography (HPLC). The mechanism of retention in SFC is unclear and a number of competing interactions can be considered to be occurring. studies into the retention of test solutes exhibiting a variety of functional groups in different systems have been carried out using a simple home-made SFC system constructed using a pye-Unicam GC oven and a HPLC pump. [Continues.