Derivatives of Diels-Alder adducts of thebaine and of 14-hydroxy codeinone provide some of the most potent analgesics in the morphine-thebaine group of alkaloids. As an extension to the range of available compounds, the preparation of further modified thebaines and 14-hydroxy codeinone was investigated. [Continues.
Research Council a sum of money to be used for the study of drug addiction. Accordingly, the Researc...
VOLUME. 1: Published papers1. The morphine group. Part 1. || 2. The morphine group. Part 2. || ...
An efficient, practical and expeditious method has been developed for the oxidation of thebaine to ...
Derivatives of both 14-hydroxycodeinone and the Diels-Alder adducts of thebaine provide some of the ...
The synthesis of codeinone enol ethers from thebaine, via acetals of 14beta-bromocodeinone, has been...
A series of 14-substituted codeine derivatives were prepared for pharmacological study by sodium bor...
The reaction of tetranitromethane with thebaine (4) has been studied and alternative routes to 14bet...
The present thesis describes our latest results in the chemistry of morphine alkaloids. An enantiodi...
textA series of morphinan-based compounds inspired by the semi-synthetic opioid metopon have been sy...
In the last decades, the number of patients undergoing pain relief for chronic or degenerative disea...
Nitrosation of thebaine using nitrosyl chloride, pentyl nitrite and nitrosyl sulphuric acid was inve...
The present thesis describes our latest results in the chemistry of morphine alkaloids. An enantiod...
A new route to the synthesis of 14beta-alkylmorphinans, of interest as potential analgesics, has bee...
Ethylketocyclazocine (EKC), a benzomorphan drug with a 10-oxo group, binds preferentially to kappa o...
text(-) Codeine, (-) morphine, and their semi-synthetic derivatives play an integral role in medicin...
Research Council a sum of money to be used for the study of drug addiction. Accordingly, the Researc...
VOLUME. 1: Published papers1. The morphine group. Part 1. || 2. The morphine group. Part 2. || ...
An efficient, practical and expeditious method has been developed for the oxidation of thebaine to ...
Derivatives of both 14-hydroxycodeinone and the Diels-Alder adducts of thebaine provide some of the ...
The synthesis of codeinone enol ethers from thebaine, via acetals of 14beta-bromocodeinone, has been...
A series of 14-substituted codeine derivatives were prepared for pharmacological study by sodium bor...
The reaction of tetranitromethane with thebaine (4) has been studied and alternative routes to 14bet...
The present thesis describes our latest results in the chemistry of morphine alkaloids. An enantiodi...
textA series of morphinan-based compounds inspired by the semi-synthetic opioid metopon have been sy...
In the last decades, the number of patients undergoing pain relief for chronic or degenerative disea...
Nitrosation of thebaine using nitrosyl chloride, pentyl nitrite and nitrosyl sulphuric acid was inve...
The present thesis describes our latest results in the chemistry of morphine alkaloids. An enantiod...
A new route to the synthesis of 14beta-alkylmorphinans, of interest as potential analgesics, has bee...
Ethylketocyclazocine (EKC), a benzomorphan drug with a 10-oxo group, binds preferentially to kappa o...
text(-) Codeine, (-) morphine, and their semi-synthetic derivatives play an integral role in medicin...
Research Council a sum of money to be used for the study of drug addiction. Accordingly, the Researc...
VOLUME. 1: Published papers1. The morphine group. Part 1. || 2. The morphine group. Part 2. || ...
An efficient, practical and expeditious method has been developed for the oxidation of thebaine to ...