Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

WOS: 000306524200007PubMed ID: 21823837In this study, some N-[4-(Benzothiazole-2-yl)phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. The anticancer activities of the compounds obtained were investigated. It was observed that some of the compounds, namely 25 and 38, showed notable anticancer activity.Eskisehir Osmangazi University [ESOGU/200819010]This work was supported by the Commission of Scientific Research Projects of Eskisehir Osmangazi University (ESOGU/200819010). The authors gratefully acknowledge the financial support by Eskisehir Osmangazi University. Authors also would like to thank to National Cancer Institue (NCI), Bethesda, MD, USA for in vitro screening of our compounds in human cancer cell lines.Eskisehir Osmangazi Universit