Associations entre récepteurs opioïdes : vers de nouvelles stratégies thérapeutiques pour la douleur et l’addiction

Opioid receptors modulate numerous physiological functions. These receptors can associate each other to form a new functional entity named heteromer, which possesses specific functional properties. In vivo data suggest a crucial role for opioid heteromers in acute or chronic pain as well as addiction, pointing them as a new therapeutic target for the treatment of these pathologies