INTRODUCTION: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ultimately occlude a vessel. This may provoke ischemic pathologies such as myocardial infarction, stroke or peripheral artery diseases, which represent the major causes of death worldwide. The aim of this study was to evaluate the specificity of radiolabeled Rat-Anti-Mouse antibody (RAM.1). METHODS: We describe a method to detect platelets by using a RAM.1 coupled with the chelating agent hydrazinonicotinic acid (HYNIC) conjugated to (99m)Tc, for Single Photon Emission Computed Tomography (SPECT). To induce platelet accumulation at a site of interest, we used a mouse model of FeCl3 induced injury of the carotid artery. 90min after i...
Actuellement l'imagerie du thrombus artériel ou thrombus intra-luminal se base sur l'imagerie morpho...
The development of radiolabeled small peptide or peptidomimetic ligands can bind platelets and their...
Imaging of acute thrombus, especially the very prevalent condition of acute deep vein thrombosis is ...
Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ulti...
Introduction: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...
BACKGROUND: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...
Background: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...
BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
Radioisotope-labelled nanoparticles permit novel applications in molecular imaging, while recent dev...
Since atherosclerotic plaques are small and sparse, their non-invasive detection via PET imaging req...
BACKGROUND: Platelets are the key to thrombus formation and play a role in the development of athero...
BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
Background: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
The efficacy of thrombolysis is inversely correlated with thrombus age. During early thrombogenesis,...
analysis.<0.01).. These results encourage further studies elucidating the r...
Actuellement l'imagerie du thrombus artériel ou thrombus intra-luminal se base sur l'imagerie morpho...
The development of radiolabeled small peptide or peptidomimetic ligands can bind platelets and their...
Imaging of acute thrombus, especially the very prevalent condition of acute deep vein thrombosis is ...
Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ulti...
Introduction: Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus...
BACKGROUND: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...
Background: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured ...
BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
Radioisotope-labelled nanoparticles permit novel applications in molecular imaging, while recent dev...
Since atherosclerotic plaques are small and sparse, their non-invasive detection via PET imaging req...
BACKGROUND: Platelets are the key to thrombus formation and play a role in the development of athero...
BACKGROUND: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
Background: Early and non-invasive detection of platelets on micro atherothrombosis provides a means...
The efficacy of thrombolysis is inversely correlated with thrombus age. During early thrombogenesis,...
analysis.<0.01).. These results encourage further studies elucidating the r...
Actuellement l'imagerie du thrombus artériel ou thrombus intra-luminal se base sur l'imagerie morpho...
The development of radiolabeled small peptide or peptidomimetic ligands can bind platelets and their...
Imaging of acute thrombus, especially the very prevalent condition of acute deep vein thrombosis is ...