Prevalence of osteoporosis, estimation of probability of fracture and bone metabolism study in patients with newly diagnosed prostate cancer in the health area of Lugo

To study the prevalence of osteoporosis and fracture probability in patients diagnosed with prostate cancer. Observational descriptive transversal study. SITE: Study performed from Primary Care of Lugo in collaboration with Rheumatology and Urology Services of our referral hospital. Patients diagnosed with prostate cancer without bone metastatic disease from January to December 2012. Epidemiologic, clinical, laboratory and densitometric variables involved in osteoporosis were collected. The likelihood of fracture was estimated by FRAX(®) Tool. Eighty-three patients met the inclusion criteria. None was excluded. The average age was 67 years. The Body Mass Index was 28.28. Twenty-five patients (30.1%) had previous osteoporotic fractures. Other prevalent risk factors were alcohol (26.5%) and smoking (22.9%). Eighty-two subjects had vitamin D below normal level (98.80%). Femoral Neck densitometry showed that 8.9% had osteoporosis and 54% osteopenia. The average fracture risk in this population, estimated by FRAX(®), was 2.63% for hip fracture and 5.28% for major fracture. Cut level for FRAX(®) major fracture value without DXA >5% and ≥7.5% proposed by Azagra et al. showed 24 patients (28.92%) and 8 patients (9.64%) respectively. The prevalence of osteoporosis in this population was very high. The more frequent risk factors associated with osteoporosis were: previous osteoporotic fracture, alcohol consumption, smoking and family history of previous fracture. The probability of fracture using femoral neck FRAX(®) tool was low. Vitamin D deficiency was very common (98.8%).Objetivo: Estudiar la prevalencia de osteoporosis y probabilidad de fractura en pacientes diagnosticados de cáncer de próstata. Diseño: Estudio observacional, descriptivo y transversal. Emplazamiento: Estudio realizado desde atención primaria del área sanitaria de Lugo en colaboración con los servicios de Reumatología y Urología de nuestro hospital de referencia. Participantes: Pacientes diagnosticados de cáncer de próstata sin enfermedad metastásica ósea, desde enero a diciembre del año 2012. Mediciones principales: Se recogieron variables epidemiológicas, clínicas, analíticas y densitométricas implicadas en la osteoporosis. Se estimó la probabilidad de fractura mediante la herramienta FRAX® . Resultados: Ochenta y tres pacientes cumplieron los criterios de inclusión. Ninguno fue excluido. La edad media fue de 67 años. El índice de masa corporal fue de 28,28. Veinticinco pacientes (30,1%) presentaban fracturas osteoporóticas previas. Otros factores de riesgo prevalentes fueron el alcohol (26,5%) y el tabaco (22,9%). Ochenta y dos sujetos presentaban valores de vitamina D por debajo de lo normal (98,80%). La densitometría de cuello femoral mostró que el 8,9% presentaron osteoporosis y el 54% osteopenia