Obesity has been considered a risk factor for osteoarthritis and it is usually accepted that obesity contributes to the development and progression of osteoarthritis by increasing mechanical load of the joints. Nevertheless, recent advances in the physiology of white adipose tissue evidenced that fat cells produce a plethora of factors, called adipokines, which have a critical role in the development of ostearthritis, besides to mechanical effects. In this paper, we review the role of adipokines and highlight the cellular and molecular mechanisms at play in osteoarthritis elicited by adipokines. We also emphasize how defining the role of adipokines has broadned our understanding of the diversity of factors involved in the genesis and progre...
The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue ...
Osteoarthritis (OA) is a multifactorial disease. Different risk factors have been identified such as...
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue ...
Osteoarthritis is a high-incidence painful and debilitating disease characterized by progressive deg...
The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue ...
AbstractObesity has been associated with an increased risk of osteoarthritis (OA). However, the mech...
BACKGROUND: Osteoarthritis is a prevalent disabling disease\ud linked to obesity. The research commu...
Adipose secreted cytokines are thought to contribute to pro-inflammatory state seen commonly in obes...
Osteoarthritis (OA) is the most common form of arthritis worldwide. It results in chronic pain, func...
Osteoarthritis (OA) is a heterogeneous and multifactorial process of chronic degenerative joint diso...
Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally affects i...
infrapatellar fat pad (IPFP) and synovium of osteoarthritis patients and healthy individuals Osteoar...
SummaryObjectiveTo analyze the distribution of leptin, adiponectin and resistin between paired serum...
8th International Meeting of Lorraine Pole of Cartilage Engineering, Vandaeuvre Les Nancy, FRANCE, S...
Inflammation is a complex mechanism of cell/tissue responses to injuries triggered by multiple cause...
The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue ...
Osteoarthritis (OA) is a multifactorial disease. Different risk factors have been identified such as...
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue ...
Osteoarthritis is a high-incidence painful and debilitating disease characterized by progressive deg...
The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue ...
AbstractObesity has been associated with an increased risk of osteoarthritis (OA). However, the mech...
BACKGROUND: Osteoarthritis is a prevalent disabling disease\ud linked to obesity. The research commu...
Adipose secreted cytokines are thought to contribute to pro-inflammatory state seen commonly in obes...
Osteoarthritis (OA) is the most common form of arthritis worldwide. It results in chronic pain, func...
Osteoarthritis (OA) is a heterogeneous and multifactorial process of chronic degenerative joint diso...
Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally affects i...
infrapatellar fat pad (IPFP) and synovium of osteoarthritis patients and healthy individuals Osteoar...
SummaryObjectiveTo analyze the distribution of leptin, adiponectin and resistin between paired serum...
8th International Meeting of Lorraine Pole of Cartilage Engineering, Vandaeuvre Les Nancy, FRANCE, S...
Inflammation is a complex mechanism of cell/tissue responses to injuries triggered by multiple cause...
The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue ...
Osteoarthritis (OA) is a multifactorial disease. Different risk factors have been identified such as...
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue ...