International audienceThe Open Computing Language (OpenCL) is increasingly adopted for programming processors with reconfigurable hardware acceleration. The 5G telecommunication infrastructure , imposing strong latency constraints on the managed communications , may benefit from OpenCL-designed accelerated processing. This paper presents the first study to evaluate OpenCL hardware acceleration in the context of a 5G base station physical layer. The implementation and optimization process to accelerate the Orthogonal Frequency Division Multiplexing (OFDM) part of the 5G downlink is conducted on a high-end Field Programmable Gate Array (FPGA). We show that the proposed OpenCL implementation complies with the 5G processing timing requirements ...