The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has become clear that in the field of liver disease specific glycomic patters are present in specific disease states, which has led to the development of diagnostic biomarkers. In this manuscript, we will describe two new applications of this technology for the development of prognostic biomarkers. The first biomarker is associated with the risk of hepatocellular carcinoma development in patients with compensated cirrhosis. The second biomarker is present in perfusate and is related to the risk of primary non function occurrence after liver transplantation. The technology used for these biomarkers could easily be implemented on routine capillary...
Kam, Kin Ting.Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.Includes bibliographical refer...
Background: We previously reported on serum N-glycans as markers for the diagnosis of cirrhosis in p...
We previously proposed a high-throughput strategy to discover serological biomarker candidates of ca...
The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has...
Glycomics research has become a versatile approach to several scientific problems, interfacing multi...
Background. Prediction of outcome after liver transplantation (LT) is limited by the lack of robust ...
Objectives Patients with chronic hepatitis C virus (HCV) infection have a genuine risk of developing...
Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome procedure that ...
The early diagnosis of hepatocellular carcinoma (HCC) is of great clinical desirable due to lack of ...
Aim. The present study aimed to evaluate the changes in the serum N-glycome profiles in chronic hepa...
We evaluated the use of blood serum N-glycan fingerprinting as a tool for the diagnosis of hepatocel...
Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome procedure that ...
Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their struct...
We developed a 3 h procedure for preparing serum N-glycans and labeling them with 8-aminopyrene-1,3,...
Purpose: Alteration of liver function during progression of hepatocellular carcinoma (HCC) and cirrh...
Kam, Kin Ting.Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.Includes bibliographical refer...
Background: We previously reported on serum N-glycans as markers for the diagnosis of cirrhosis in p...
We previously proposed a high-throughput strategy to discover serological biomarker candidates of ca...
The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has...
Glycomics research has become a versatile approach to several scientific problems, interfacing multi...
Background. Prediction of outcome after liver transplantation (LT) is limited by the lack of robust ...
Objectives Patients with chronic hepatitis C virus (HCV) infection have a genuine risk of developing...
Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome procedure that ...
The early diagnosis of hepatocellular carcinoma (HCC) is of great clinical desirable due to lack of ...
Aim. The present study aimed to evaluate the changes in the serum N-glycome profiles in chronic hepa...
We evaluated the use of blood serum N-glycan fingerprinting as a tool for the diagnosis of hepatocel...
Liver fibrosis is currently assessed by liver biopsy, a costly and rather cumbersome procedure that ...
Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their struct...
We developed a 3 h procedure for preparing serum N-glycans and labeling them with 8-aminopyrene-1,3,...
Purpose: Alteration of liver function during progression of hepatocellular carcinoma (HCC) and cirrh...
Kam, Kin Ting.Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.Includes bibliographical refer...
Background: We previously reported on serum N-glycans as markers for the diagnosis of cirrhosis in p...
We previously proposed a high-throughput strategy to discover serological biomarker candidates of ca...