Add to ORKGRecent discoveries demonstrate a critical role for circadian rhythms and sleep in immune system homeostasis. Both innate and adaptive immune responses - ranging from leukocyte mobilization, trafficking, and chemotaxis to cytokine release and T cell differentiation -are mediated in a time of day-dependent manner. The National Institutes of Health (NIH) recently sponsored an interdisciplinary workshop, Sleep Insufficiency, Circadian Misalignment, and the Immune Response, to highlight new research linking sleep and circadian biology to immune function and to identify areas of high translational potential. This Review summarizes topics discussed and highlights immediate opportunities for delineating clinically relevant connections among biolo...
Microbial infection poses a threat to organismal homeostasis and therefore must be efficiently count...
The immune system is regulated by circadian clocks within the brain and immune cells. Environmental ...
Circadian rhythms have a regulatory effect on immune function. The immune system has circadian fluct...
Circadian clocks regulate the daily timing of many of our physiological, metabolic and biochemical f...
Although several papers have described circadian regulation of the immune function, our goal is to a...
The circadian clock regulates numerous key physiological processes and maintains cellular, tissue, a...
Circadian timekeeping is a ubiquitous feature of all eukaryotes which allows for the imposition of a...
Rhythms in immunity manifest in multiple ways, but perhaps most prominently by the recurrent onset o...
Abstract The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the pa...
Circadian rhythms are a ubiquitous feature of virtually all living organisms, regulating a wide dive...
This is an open access article distributed under the Creative Commons Attribution License, which per...
The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were the first to...
The circadian rhythm (CR) is a fundamental biological process regulated by the Earth's rotation and ...
Several parameters of the immune system exhibit oscillations with a period of approximately 24 hours...
Immune parameters change with time of day and disruption of circadian rhythms has been linked to inf...
Microbial infection poses a threat to organismal homeostasis and therefore must be efficiently count...
The immune system is regulated by circadian clocks within the brain and immune cells. Environmental ...
Circadian rhythms have a regulatory effect on immune function. The immune system has circadian fluct...
Circadian clocks regulate the daily timing of many of our physiological, metabolic and biochemical f...
Although several papers have described circadian regulation of the immune function, our goal is to a...
The circadian clock regulates numerous key physiological processes and maintains cellular, tissue, a...
Circadian timekeeping is a ubiquitous feature of all eukaryotes which allows for the imposition of a...
Rhythms in immunity manifest in multiple ways, but perhaps most prominently by the recurrent onset o...
Abstract The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the pa...
Circadian rhythms are a ubiquitous feature of virtually all living organisms, regulating a wide dive...
This is an open access article distributed under the Creative Commons Attribution License, which per...
The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were the first to...
The circadian rhythm (CR) is a fundamental biological process regulated by the Earth's rotation and ...
Several parameters of the immune system exhibit oscillations with a period of approximately 24 hours...
Immune parameters change with time of day and disruption of circadian rhythms has been linked to inf...
Microbial infection poses a threat to organismal homeostasis and therefore must be efficiently count...
The immune system is regulated by circadian clocks within the brain and immune cells. Environmental ...
Circadian rhythms have a regulatory effect on immune function. The immune system has circadian fluct...