Bovine leukemia virus can be classified into seven genotypes: Evidence for the existence of two novel clades
- Rodriguez, Sabrina M.
- Golemba, Marcelo Darío
- Campos, Rodolfo Hector
- Trono, Karina Gabriela
- Jones, Leandro Roberto
DOIAbstract
Previous studies have classified the env sequences of bovine leukemia virus (BLV) provirus from different locations worldwide into between two and four genetic groupings. These different studies gave unique names to the identified groups and no study has yet integrated all the available sequences. Thus, we hypothesized that many of the different groups previously identified actually correspond to a limited group of genotypes that are unevenly distributed worldwide. To examine this hypothesis, we sequenced the env gene from 28 BLV field strains and compared these sequences to 46 env sequences that represent all the genetic groupings already identified. By using phylogenetic analyses, we recovered six clades, or genotypes, that we have called...