Abstract The activity of the growth hormone (GH) axis is altered by critical illness. In the acute phase, GH resistance, as reflected by increased GH and decreased insulin-like growth factor-I (IGF-I), mimics fasting-induced changes in health. Although early full feeding in ICU has long been assumed to prevent muscle wasting and weakness, the EPaNIC RCT observed fewer complications and faster recovery with accepting the macronutrient deficit in the first ICU week, as compared with early full feeding, including less acquired muscle weakness [1,2]. We previously observed that accepting the early macronutrient deficit attenuated rather than aggravated the rise in GH as compared with early full feeding [3]. We have now further characterized it...
Abstract: BackgroundCritical illness is hallmarked by severe stress and organ damage. Fibroblast gro...
Background: Early mobilization improves physical independency of critically ill patients at hospital...
AimThe study aimed to investigate the effect of early mobilization combined with early nutrition (EM...
CONTEXT: Changes in the GH axis during critical illness resemble fasting in healthy adults and contr...
OBJECTIVE: The aim was to study the relationship between growth hormone (GH) and insulin-like growth...
Major advances in intensive care medicine have allowed great improvements in the outcome of critical...
Muscle wasting is common in severe critical illness. ICU-acquired weakness (ICU-AW) contributes to a...
© 2017, Pharmamed Mado Ltd. All rights reserved. Mortality rates from critical illness are decreasin...
Despite improvements in critical illness survival rates with recent developments in medical care, ma...
Context:Both critical illness and fasting induce low circulating thyroid hormone levels in the absen...
Background & aims: Optimal nutritional support during the acute phase of critical illness remains co...
OBJECTIVE: The goal of enhanced nutrition in critically ill patients is to improve outcome by reduci...
Muscle wasting occurs rapidly within days of an admission to the intensive care unit (ICU). Concomit...
Background: Cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1 beta and IL-6, ...
BACKGROUND:Muscle wasting in the critically ill is up to 2% per day and delays patient recovery and ...
Abstract: BackgroundCritical illness is hallmarked by severe stress and organ damage. Fibroblast gro...
Background: Early mobilization improves physical independency of critically ill patients at hospital...
AimThe study aimed to investigate the effect of early mobilization combined with early nutrition (EM...
CONTEXT: Changes in the GH axis during critical illness resemble fasting in healthy adults and contr...
OBJECTIVE: The aim was to study the relationship between growth hormone (GH) and insulin-like growth...
Major advances in intensive care medicine have allowed great improvements in the outcome of critical...
Muscle wasting is common in severe critical illness. ICU-acquired weakness (ICU-AW) contributes to a...
© 2017, Pharmamed Mado Ltd. All rights reserved. Mortality rates from critical illness are decreasin...
Despite improvements in critical illness survival rates with recent developments in medical care, ma...
Context:Both critical illness and fasting induce low circulating thyroid hormone levels in the absen...
Background & aims: Optimal nutritional support during the acute phase of critical illness remains co...
OBJECTIVE: The goal of enhanced nutrition in critically ill patients is to improve outcome by reduci...
Muscle wasting occurs rapidly within days of an admission to the intensive care unit (ICU). Concomit...
Background: Cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1 beta and IL-6, ...
BACKGROUND:Muscle wasting in the critically ill is up to 2% per day and delays patient recovery and ...
Abstract: BackgroundCritical illness is hallmarked by severe stress and organ damage. Fibroblast gro...
Background: Early mobilization improves physical independency of critically ill patients at hospital...
AimThe study aimed to investigate the effect of early mobilization combined with early nutrition (EM...