Genetically distinct GABAergic interneuron subtypes play diverse roles in cortical circuits. Previous studies revealed thatmicroRNAs (miRNAs) are differentially expressed in cortical interneuron subtypes, and are essential for the normalmigration, maturation, and survival of medial ganglionic eminence-derived interneuron subtypes. How miRNAs function invasoactive intestinal peptide expressing (VIP+) interneurons derived from the caudal ganglionic eminence remains elusive.Here, we conditionally removedDicerin postmitotic VIP+interneurons to block miRNA biogenesis. We found that theintrinsic and synaptic properties of VIP+interneurons and pyramidal neurons were concordantly affected prior to aprogressive loss of VIP+interneurons. In vivo reco...
miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptoge...
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-transcriptional reg...
<div><h3>Background</h3><p>The small non-protein-coding microRNAs (miRNAs) have emerged as critical ...
Genetically distinct GABAergic interneuron subtypes play diverse roles in cortical circuits. Previou...
The regulation of the balance between excitatory and inhibitory (E/I) neuronal synaptic transmission...
GABAergic interneurons play important roles in cortical circuit development. However, there are mult...
MicroRNAs (miRNAs) are critical regulators of nervous system function, and in vivo knockout studies ...
GABAergic interneurons play important roles in cortical circuit development. However, there are mult...
The RNase Dicer is essential for the maturation of most microRNAs, a molecular system that plays an ...
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation...
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation...
AbstractMicroRNAs are small non-coding RNAs that inhibit protein expression post-transcriptionally. ...
Summary: Adult neurogenesis requires the precise control of neuronal versus astrocyte lineage determ...
BACKGROUND: The small non-protein-coding microRNAs (miRNAs) have emerged as critical regulators of n...
MicroRNAs (miRNAs) are evolutionarily conserved, 18- to 25-nucleotide, non-protein coding transcript...
miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptoge...
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-transcriptional reg...
<div><h3>Background</h3><p>The small non-protein-coding microRNAs (miRNAs) have emerged as critical ...
Genetically distinct GABAergic interneuron subtypes play diverse roles in cortical circuits. Previou...
The regulation of the balance between excitatory and inhibitory (E/I) neuronal synaptic transmission...
GABAergic interneurons play important roles in cortical circuit development. However, there are mult...
MicroRNAs (miRNAs) are critical regulators of nervous system function, and in vivo knockout studies ...
GABAergic interneurons play important roles in cortical circuit development. However, there are mult...
The RNase Dicer is essential for the maturation of most microRNAs, a molecular system that plays an ...
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation...
Dicer-dependent noncoding RNAs, including microRNAs (miRNAs), play an important role in a modulation...
AbstractMicroRNAs are small non-coding RNAs that inhibit protein expression post-transcriptionally. ...
Summary: Adult neurogenesis requires the precise control of neuronal versus astrocyte lineage determ...
BACKGROUND: The small non-protein-coding microRNAs (miRNAs) have emerged as critical regulators of n...
MicroRNAs (miRNAs) are evolutionarily conserved, 18- to 25-nucleotide, non-protein coding transcript...
miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptoge...
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-transcriptional reg...
<div><h3>Background</h3><p>The small non-protein-coding microRNAs (miRNAs) have emerged as critical ...