The Lago Superiore Unit (LSU, Monviso Massif, Italian Western Alps) is a section of fossil oceanic lithosphere equilibrated to eclogite facies conditions (550 °C – 2.8 GPa) during Alpine subduction (45–40 Ma). It is cut by two major shear zones, namely the Intermediate (ISZ) and Lower Shear Zone (LSZ), mostly consisting of serpentinite. The lowermost, serpentine-rich, section of the Lago Superiore Unit, the Basal Serpentinite, separates the HP ophiolite domain from the underlying continental Dora-Maira Unit. Here we show that the LSZ and the Basal Serpentinite were active at different stages of the subduction and exhumation history of the complex. Most of retrograde deformation and mineral re-equilibration were localized in the LSZ. Chann...