Exome sequencing data analysis

Whole exome sequencing, owing to its low cost and computational burden, has become the standard for causal gene detection in disease and treatment management. This article provides a brief overview of exome data generation and discusses the computational pipeline involved in utilizing exome sequencing data to identify specific variants, as well as its applications in clinical settings. In particular, we present the steps necessary to facilitate relevant data analysis practices, and survey relevant computational tools to streamline these analyses. This article is aimed to serve as a quick guide for researchers working on exome sequencing data