Three recent studies provide new insight into the mechanisms that promote the differentiation of antigen-primed T cells into the follicular helper T (Tfh) lineage, revealing a key role for the transcription factor TCF-1 in the regulation of the Bc16-Blimp-1 axis that mediates the divergence between the Tfh and the TM lineages
International audienceT cell development is orchestrated by transcription factors that regulate the ...
International audienceInnate lymphoid cells (ILCs) play important functions in immunity and tissue h...
SummaryFollicular helper T (Tfh) cells comprise an important subset of helper T cells; however, thei...
International audienceT follicular helper (TFH) and T helper 1 (Th1) cells generated after viral inf...
Helping B cells and antibody responses is a major function of CD4+T helper cells. Follicular helper ...
SummaryT follicular helper (TFH) and T helper 1 (Th1) cells generated after viral infections are cri...
The vertebrate thymus provides an inductive environment for T-cell development. Within the thymus, N...
© 2021 Amania Anwar SheikhT follicular helper cells (TFH) are specialised CD4+ T cells that promote ...
T cell development within the thymus is initiated by settling of rare multipotent progenitors. Signa...
During viral infection, immune cells coordinate the induction of inflammatory responses that clear i...
Understanding the developmental mechanisms of follicular helper T cells (TFH cells) in humans is rel...
Follicular helper T cells have recently emerged as a separate CD4 + T helper lineage specialised in ...
Follicular helper T (Tfh) cells are specialized providers of T cell help to B cells, and are essenti...
Differentiation of cells into distinct cell types and tis-sues is governed by complex developmental ...
Although transcriptional programs associated with T-cell specification and commitment have been desc...
International audienceT cell development is orchestrated by transcription factors that regulate the ...
International audienceInnate lymphoid cells (ILCs) play important functions in immunity and tissue h...
SummaryFollicular helper T (Tfh) cells comprise an important subset of helper T cells; however, thei...
International audienceT follicular helper (TFH) and T helper 1 (Th1) cells generated after viral inf...
Helping B cells and antibody responses is a major function of CD4+T helper cells. Follicular helper ...
SummaryT follicular helper (TFH) and T helper 1 (Th1) cells generated after viral infections are cri...
The vertebrate thymus provides an inductive environment for T-cell development. Within the thymus, N...
© 2021 Amania Anwar SheikhT follicular helper cells (TFH) are specialised CD4+ T cells that promote ...
T cell development within the thymus is initiated by settling of rare multipotent progenitors. Signa...
During viral infection, immune cells coordinate the induction of inflammatory responses that clear i...
Understanding the developmental mechanisms of follicular helper T cells (TFH cells) in humans is rel...
Follicular helper T cells have recently emerged as a separate CD4 + T helper lineage specialised in ...
Follicular helper T (Tfh) cells are specialized providers of T cell help to B cells, and are essenti...
Differentiation of cells into distinct cell types and tis-sues is governed by complex developmental ...
Although transcriptional programs associated with T-cell specification and commitment have been desc...
International audienceT cell development is orchestrated by transcription factors that regulate the ...
International audienceInnate lymphoid cells (ILCs) play important functions in immunity and tissue h...
SummaryFollicular helper T (Tfh) cells comprise an important subset of helper T cells; however, thei...