Add to ORKGThe studies in this doctoral thesis focus on thyroid hormone transporters, specifically monocarboxylate transporter (MCT) 8. The studies cover the whole spectrum from molecular studies on MCT8 structure and function to a phase II clinical trial with the thyroid hormone analogue Triac in patients with MCT8 deficiency
Thyroid hormone (TH) is essential for the proper development of numerous tissues, notably the brain....
Thyroid hormone is important for development of various tissues, in particular brain, and for regula...
Background: As a prerequisite for thyroid hormone (TH) metabolism and action TH has to be transporte...
Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid ...
Genetic defects in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MC...
The effects of thyroid hormone (TH) on development and metabolism are exerted at the cellular level....
textabstractThyroid hormone is a pleiotropic hormone with widespread biological actions. For instanc...
Thyroid hormone metabolism and action are largely intracellular events that require transport of iod...
textabstractThe studies presented in this thesis demonstrate that MCT8 is a transmembrane protein th...
Thyroid hormone (TH) is crucial for the development of different organs, in particular the brain, as...
Genetic defects in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MC...
Monocarboxylate transporter 8 (MCT8, SLC16A2) is a thyroid hormone (TH) transmembrane transport prot...
The mechanism of thyroid hormone (TH) secretion from the thyroid gland into the bloodstream is still...
Objective Monocarboxylate transporter 8 (MCT8) is an essential thyroid hormone (TH) transporter as h...
Allan-Herndon-Dudley syndrome is a rare disease caused by inactivating mutations in the SLC16A2 gene...
Thyroid hormone (TH) is essential for the proper development of numerous tissues, notably the brain....
Thyroid hormone is important for development of various tissues, in particular brain, and for regula...
Background: As a prerequisite for thyroid hormone (TH) metabolism and action TH has to be transporte...
Thyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid ...
Genetic defects in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MC...
The effects of thyroid hormone (TH) on development and metabolism are exerted at the cellular level....
textabstractThyroid hormone is a pleiotropic hormone with widespread biological actions. For instanc...
Thyroid hormone metabolism and action are largely intracellular events that require transport of iod...
textabstractThe studies presented in this thesis demonstrate that MCT8 is a transmembrane protein th...
Thyroid hormone (TH) is crucial for the development of different organs, in particular the brain, as...
Genetic defects in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MC...
Monocarboxylate transporter 8 (MCT8, SLC16A2) is a thyroid hormone (TH) transmembrane transport prot...
The mechanism of thyroid hormone (TH) secretion from the thyroid gland into the bloodstream is still...
Objective Monocarboxylate transporter 8 (MCT8) is an essential thyroid hormone (TH) transporter as h...
Allan-Herndon-Dudley syndrome is a rare disease caused by inactivating mutations in the SLC16A2 gene...
Thyroid hormone (TH) is essential for the proper development of numerous tissues, notably the brain....
Thyroid hormone is important for development of various tissues, in particular brain, and for regula...
Background: As a prerequisite for thyroid hormone (TH) metabolism and action TH has to be transporte...