The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.</p
Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large ribonucleoprote...
Most human genes are composed of coding sequences (exons) that are interrupted by non-coding sequenc...
Pre-mRNA splicing is an essential step in eukaryotic gene expression. Splicing is catalyzed by the ...
The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed...
Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP spl...
Controlled execution of transcription and pre-mRNA splicing is crucial for proper gene expression. T...
Studies from several laboratories during the past few years have increased our understanding towards...
Most eukaryotic pre-mRNAs contain non-coding sequences (introns) that must be removed in order to ac...
The spliceosome is a large RNA‐protein complex that catalyses the removal of introns from nuclear pr...
Pre-mRNA splicing occurs in a macromolecular complex called the spliceosome. Efforts to isolate spli...
All eukaryotic protein-coding genes are transcribed by RNA polymerase II (pol II), and each mRNA is ...
HeLa cell nuclei were permeabilized and reconstituted with nuclear extract to identify soluble nucle...
Precursor messenger RNA (pre-mRNA) splicing is a critical step in the posttranscriptional regulation...
Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within...
Precursor messenger RNA splicing is a highly regulated process, mediated by a complex RNA-protein ma...
Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large ribonucleoprote...
Most human genes are composed of coding sequences (exons) that are interrupted by non-coding sequenc...
Pre-mRNA splicing is an essential step in eukaryotic gene expression. Splicing is catalyzed by the ...
The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed...
Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP spl...
Controlled execution of transcription and pre-mRNA splicing is crucial for proper gene expression. T...
Studies from several laboratories during the past few years have increased our understanding towards...
Most eukaryotic pre-mRNAs contain non-coding sequences (introns) that must be removed in order to ac...
The spliceosome is a large RNA‐protein complex that catalyses the removal of introns from nuclear pr...
Pre-mRNA splicing occurs in a macromolecular complex called the spliceosome. Efforts to isolate spli...
All eukaryotic protein-coding genes are transcribed by RNA polymerase II (pol II), and each mRNA is ...
HeLa cell nuclei were permeabilized and reconstituted with nuclear extract to identify soluble nucle...
Precursor messenger RNA (pre-mRNA) splicing is a critical step in the posttranscriptional regulation...
Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within...
Precursor messenger RNA splicing is a highly regulated process, mediated by a complex RNA-protein ma...
Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large ribonucleoprote...
Most human genes are composed of coding sequences (exons) that are interrupted by non-coding sequenc...
Pre-mRNA splicing is an essential step in eukaryotic gene expression. Splicing is catalyzed by the ...
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