Effects of obesity on cholesterol metabolism and its implications for healthy ageing.

This article has been published in a revised form in Nutrition Research Reviews [https://doi.org/10.1017/S0954422419000258]. This version is free to view and download for private research and study only. Not for re-distribution or re-use. © copyright holder.The last few decades have witnessed a global rise in the number of older people. Despite this demographic shift, morbidity within this population group is high. Many factors influence healthspan; however an obesity pandemic is emerging as a significant determinant of older peoples’ health. It is well established obesity adversely effects several metabolic systems. However, due to its close association with overall cardiometabolic health, the impact obesity has on cholesterol metabolism needs to be recognised. The aim of this review is to critically discuss the effects obesity has on cholesterol metabolism and to reveal its significance for healthy ageing