Add to ORKGWorking at the International Centre for Genetic Engeneering and Biotechnology, where I started my Ph.D thesis in October '96 I have directed my research activity to the immunotherapy of B-cell malignancies by DNA vaccination. I have developed an efficent vaccination strategy to induce protection in the BCL1 lynphoma model and characterized all the elements of the antigen encoding plasmid that contribute to the induction of the immune response. In addition, I have investigated the structural requirements of the idiotypic/anti-Idiotypic interaction following scFv DNA vaccination. Thuis analysis revealed that the polyclonal anti-Id immune response induced by scFv DNA vaccination is exclusively directed against conformational combined epitopes....
Vaccination of BALB/c mice with purified idiotypic IgM derived from the BCL1 lymphoma generates a sp...
Vaccination against target antigens expressed by cancer cells has now become a realistic goal. DNA v...
Abstract: DNA vaccination, or genetic immuniza-tion, is a novel vaccine technology that has great po...
Working at the International Centre for Genetic Engeneering and Biotechnology, where I started my Ph...
DNA vaccines induce immune responses against encoded proteins, and have clear potential for cancer v...
DNA vaccines induce immune responses against encoded proteins, and have clear potential for cancer v...
Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-sp...
grantor: University of TorontoPlasmid DNA vaccines represent a powerful new method of expr...
Background: Idiotopes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-sp...
Our aim is to develop DNA vaccines against haematological malignancies, with a focus on multiple mye...
Background Therapeutic idiotypic (Id) vaccination is an experimental treatment for s...
Immunization with modified immunoglobulin (Ig) idiotypes (Ids) of B-cell lymphomas is an attractive ...
The clonotypic T-cell antigen receptor (TCR) provides unique V? and Vßsequences with potential as id...
This review focuses on DNA vaccines, denoting the last two decades since the early substantiation of...
Delivery of antigens by injection of the encoding DNA allows access to multiple antigen-presenting p...
Vaccination of BALB/c mice with purified idiotypic IgM derived from the BCL1 lymphoma generates a sp...
Vaccination against target antigens expressed by cancer cells has now become a realistic goal. DNA v...
Abstract: DNA vaccination, or genetic immuniza-tion, is a novel vaccine technology that has great po...
Working at the International Centre for Genetic Engeneering and Biotechnology, where I started my Ph...
DNA vaccines induce immune responses against encoded proteins, and have clear potential for cancer v...
DNA vaccines induce immune responses against encoded proteins, and have clear potential for cancer v...
Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-sp...
grantor: University of TorontoPlasmid DNA vaccines represent a powerful new method of expr...
Background: Idiotopes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-sp...
Our aim is to develop DNA vaccines against haematological malignancies, with a focus on multiple mye...
Background Therapeutic idiotypic (Id) vaccination is an experimental treatment for s...
Immunization with modified immunoglobulin (Ig) idiotypes (Ids) of B-cell lymphomas is an attractive ...
The clonotypic T-cell antigen receptor (TCR) provides unique V? and Vßsequences with potential as id...
This review focuses on DNA vaccines, denoting the last two decades since the early substantiation of...
Delivery of antigens by injection of the encoding DNA allows access to multiple antigen-presenting p...
Vaccination of BALB/c mice with purified idiotypic IgM derived from the BCL1 lymphoma generates a sp...
Vaccination against target antigens expressed by cancer cells has now become a realistic goal. DNA v...
Abstract: DNA vaccination, or genetic immuniza-tion, is a novel vaccine technology that has great po...
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