A new biomimetic route to engineer enzymatically active mechano-responsive materials.
- Rios, C. (César)
- Longo, J. (Johan)
- Zahouani, S. (Sarah)
- Garnier, T. (Tony)
- Vogt, C. (Cédric)
- Reisch, A. (Andreas)
- Senger, B. (Bernard)
- Boulmedais, F. (Fouzia)
- Hemmerlé, J. (Joseph)
- Benmlih, K. (Karim)
- Frisch, B. (Benoît)
- Schaaf, P. (Pierre)
- Jierry, L. (Loïc)
- Lavalle, P. (Philippe)
Publication date
April 2015
DOI Publisher
Royal Society of Chemistry (RSC) Language
EnglishAbstract
Using modified β-galactosidase covalently linked to cross-linked polyelectrolyte multilayers (PEM), catalytically active materials have been designed. Their enzymatic activity can be modulated, partially in a reversible way, simply by stretching. This strategy, based on enzyme conformational changes, constitutes a new tool for the development of biocatalytic mechano-responsive materials.journal articleresearch support, non-u.s. gov't2015 Apr 04importe
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