Effect of Hemodialysis on Spirometric Measurement in Patients with Chronic Kidney Disease

Abstract:Background: Chronic kidney disease (CKD) can adversely affect the respiratory systems functions and dynamics via different mechanisms resulting from toxic metabolites. Patients with CKD require hemodialysis for survival and prior studies have been showed a controversial effects of hemodialysis on respiratory functionObjectives: The aim of the study was to investigate the acute impact of hemodialysis on spirometric parameters in patients with CKD undergoing maintenance hemodialysisPatients and methods: One hundred patients (50% male, mean age 43.2± 15 years) with CKD who underwent regular hemodialysis at the hemodialysis center at Al-Sader Teaching Hospital between January and September 2015were enrolled in the study. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC) and the FEV1/FVC ratio (FEV1%) were performed for each patient who consented to participate in the study; before the hemodialysis session and within half hour after it. SPSS was used for the statistical analysis.Results: FEV1 and FVC were showed a statistically significant improvement in their values after hemodialysis(P0.05). FEV1 and FVC were showed a significant change and increment with increased of the frequency of hemodialysis sessions (P