Efek Antibakteri Kombinasi Daun Teh Hijau (Camellia sinensis) dengan Amoksisilin pada Staphylococcus aureus atau Escherichia coli secara in vitro

Introduction: Green tea leaf (C.sinensis) can be used as a treatment of bacterial infection because it contains of anti-bacterial compounds. Antibiotics resistance is caused by using antibiotics that does not suit with indication, and does not suit with the dose. This study was purposed to define the anti-microbial activity of amoxcicillin combined with C. sinensis leaf (methanolic extract,decoction) against S. aureus and E. coli.Method: The antibacterial activities (single,combined) low dose were measured through zone of inhibition (ZOI) test with agar well diffusion method. The result of the ZOI combinations were interpreted with the Ameri-Ziaei Double Antibiotic Synergism Test (AZDAST). The data was analysed with Kolmogorov-Smirnov, followed by a non-parametric test Mann-Whitney Test, with the value of significance on p<0.05.Results: Combination of Methanolic extract of C. sinensis leaf with Amoxcicillin (EMCA) and combination of Decoction of C. sinensis leaf with Amoxcicillin (DCA) defined on S. aureus (p