In this article, a presentation is made of the events that in a priority way, included the war against the drugs in the agenda of the relations Colombia-United States, as there was a coincidence in the official positions regarding the use of psychoactive substances. An analysis is made of the way drugs became a central issue in U. S. politics and on a worldwide basis, after the changes of the sixties and the Vietnam War and how the illegal traffic took hold in Colombia very early on and, in response, a repressive governmental strategy was implemented. The coincidence of ideological arguments and the dimension of the problem prevented Colombia from devising its own stand on this issue, instead taking on the interdiction policies of the Unite...