Failure prediction of metastatic bone with osteolytic lesion in mice

25th Congress of the European Society of Biomechanics, VIENNE, AUTRICHE, 07-/07/2019 - 12/07/2019Metastatic cancer affects the skeleton [1]. Bone metastases weaken bones, and physicians have to decide the emergency of a surgical intervention. Current tools do not allow an accurate prediction of metastatic bone failure. Past studies showed that patient-specific finite element analysis (FEA) could contribute to improve this diagnosis [2]. However, in those studies, limitations were underlined (e.g. boundary conditions and mechanical properties of tumoral tissues) [2]. Therefore, the goal of this study to use an animal model for a deeper understanding of the modelling key factors