UJI EFEKTIFITAS ANTIFUNGI EKSTRAK DAUN KEMANGI (Ocimum cannum Sims.) TERHADAP PERTUMBUHAN Candida albicans SECARA IN VITRO SEBAGAI SUMBER BELAJAR BIOLOGI

Infection is a major health problem caused by inappropriate maintained of environmental cleanliness around the community. Infection can occur due to microbial growth, one of which is fungus. Candida albicans is responsible for 50% of all fungal infections caused by the genus Candida. Basil (Ocimum cannum Sims.) is one of the species in the genus Ocimum that contains alkaloids, flavonoids, saponins, and tannins and functions as an antifungal agent. The purpose of this study was to determine the effect of various concentrations of basil leaf extract (Ocimum cannum Sims.) on the growth of Candida albicans and the results of this study will be analyzed to be used as a study of Biology learning resources. The concentrations of basil leaf extract used were 12.5%, 25%, 37.5%, 50%, and 62.5%. The effect of the extract was determined by measuring the diameter of the inhibition zone. Data analysis in this study was conducted by performing the Kruskal-Wallis non-parametric test, followed by the Mann-Whitney test. Based on the results of the study, there is an effect of basil leaf extract on the growth of Candida albicans. The highest average diameter of inhibition zone is 1.19 mm that was obtained by using Basil leaf extract at the concentration of 25%, while the lowest diameter of inhibition zone is at the concentration of 37.5% by only 0.43 mm. The results of this study can be used as a study of Biology learning resources