Lymphocytes

Lymphocytes have been the main research object of the medic and toxicological sciences for the last six decades. In addition to important roles, they ply m the immune system, lymphocytes have been the primary test material often employed m pure research-focused studies that provide important contributions to our knowledge. of biochemistry, molecular biology and genomics. To give a prominent example, the majority of DNA used for sequencing of the human genome was isolated from lymphocytes of male donor blood. Today, the use of lymphocytes for research purposes is increasing, and the variety of tests performed on these cells is also diversifying each day. Lymphocyte activation assays, fluorescence-based assays for high-throughput screening of small molecules, cytotoxic T lymphocyte assays, cell proliferation assays, blastogenesis assays for T lymphocytes for identifying immunomodulatory drugs of lymphocyte extravasation and sequencing and genotoxicity assays are among the tests that lymphocytes are frequently used for. As can be readily understood, lymphocytes serve in different ways in terms of understanding the cell structure, unknown features of the immune system, genome and chromosomes