Comparison of the systemic effects of general anaesthesia and combined spinal-epidural anaesthesia during cesarean section [Sezaryenlerde kombine spinal-epidural anestezi ile genel anestezinin anne ve yenidoganda oluşturdugu sistemik etkilerin karşilaştirilmasi]

We aimed to compare the effects of isoflurane anaesthesia and combined spinal-epidural (CSE) anaesthesia on haemodynamic, maternal stress response, APGAR and neuro adaptive capacity scores (NACS) during cesarean section. Forty pregnants were divided into two groups equally. General anaesthesia was applied in group I (n=20) whereas CSE block in group II (n=20). Preoperatively, after skin incision, before and after umblical vein clamping and after 30 minutes of operation maternal blood samples were taken for determination of renin, ACTH, aldosterone, cortisole and blood gases. These tests were also repeated in new-borns before and after umblical vein clamping. New-borns'performance were assessed rising APGAR and NACS. Plasma renin, ACTH, aldosterone, cortisole and glucose levels were found higher after skin incision, before and after umblical vein clamping in group I than in group II (p<0.05). Although aldosterone and glucose levels were found similar in two groups, renin and ACTH levels were higher in both groups (p<0.05) of new-borns after umblical cord clamping than the levels before clamping. The level of cortisole was lower in group II than in group I at both period (p< 0.05). APGAR (in first minute) and NACS (in 15th and 120th minutes) scores were found higher in group II than in group I (p