This study aimed to evaluate the effects of the nitric oxide donor molsidomine on the early stages of liver damage and biochemical changes in rats with bile duct ligation (BDL). Forty prepubertal male Sprague-Dawley rats weighing 125-140 g were studied. Group 1 rats (sham-control, n = 10) were not subjected to any surgical manipulation. Group 2 rats (BDL/untreated, n = 10) were subjected to BDL but no drug was administered. Group 3 rats (BDL/L-NAME, n = 10) received a daily dose of NG-nitro-L-arginine methyl ester (L-NAME) intraperitoneally for 7 days after BDL. Group 4 rats (BDL/molsidomine, n = 10) received a daily dose of molsidomine by gastric tube for 7 days after BDL. After 1 week, biochemical and histological evaluations were perform...
Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative stress, and ...
The goal of this study was to evaluate the possible protective effects of sphingosylphosphorylcholin...
The aim of this study was to assess the effect of melatonin and acetylsalicylic acid (ASA) on hepati...
The aims of the present work were to study the effects of chronic NO inhibition on liver cirrhosis a...
License, which permits unrestricted use, distribution, and reproduction in anymedium, provided the o...
PURPOSE: To evaluate liver alterations caused by biliary obstruction and drainage. METHODS: Thirty-n...
Cholestatic liver injury following extra- or intrahepatic bile duct obstruction causes nonparenchyma...
Background/aims: We aimed to determine the progress of lipid peroxidation and ultrastructural change...
Background Intervention of the biliary system is frequently done in patients with obstructive jaundi...
WOS: 000236127500003PubMed ID: 16479127Background/Aim: Nitric oxide supplementation and antioxidant ...
The Pringle maneuver (PM) has been widely used to control blood loss during liver resection. However...
One of the most important reasons of liver destruction in obstructive jaundice is reactive oxygen de...
Objective: Bile duct ligation (BDL), chronic liver injury model, was extensively used in studying me...
PubMed ID: 16479127Background/Aim: Nitric oxide supplementation and antioxidant therapy modulate gut...
Abstract: Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative st...
Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative stress, and ...
The goal of this study was to evaluate the possible protective effects of sphingosylphosphorylcholin...
The aim of this study was to assess the effect of melatonin and acetylsalicylic acid (ASA) on hepati...
The aims of the present work were to study the effects of chronic NO inhibition on liver cirrhosis a...
License, which permits unrestricted use, distribution, and reproduction in anymedium, provided the o...
PURPOSE: To evaluate liver alterations caused by biliary obstruction and drainage. METHODS: Thirty-n...
Cholestatic liver injury following extra- or intrahepatic bile duct obstruction causes nonparenchyma...
Background/aims: We aimed to determine the progress of lipid peroxidation and ultrastructural change...
Background Intervention of the biliary system is frequently done in patients with obstructive jaundi...
WOS: 000236127500003PubMed ID: 16479127Background/Aim: Nitric oxide supplementation and antioxidant ...
The Pringle maneuver (PM) has been widely used to control blood loss during liver resection. However...
One of the most important reasons of liver destruction in obstructive jaundice is reactive oxygen de...
Objective: Bile duct ligation (BDL), chronic liver injury model, was extensively used in studying me...
PubMed ID: 16479127Background/Aim: Nitric oxide supplementation and antioxidant therapy modulate gut...
Abstract: Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative st...
Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative stress, and ...
The goal of this study was to evaluate the possible protective effects of sphingosylphosphorylcholin...
The aim of this study was to assess the effect of melatonin and acetylsalicylic acid (ASA) on hepati...