The effects of intrathecal levobupivacaine and opioid combinations in caesarean operations [Sezaryen operasyonlarinda intratekal levobupivakaine eklenen fentanil ve morfin kombinasyonlarinin etkilerinin karşilatirmasi]

Aim: We aimed to investigate the effects of levobupivacaine, fentanyl and morphine's different intrathecal combinations on parturients planned to have elective caesarean operation with spinal anesthesia. We have also investigated the effects of these combinations on newborns. Material and Methods: One hundred and twenty parturients of ASA physical status I-II planned to have Caesarean operation enrolled in the study. Parturients randomized into four groups and Group L received 12 mg 0.5% levobupivacaine, Group LF received 10 mg 0.5% + 12.5 pg fentanyl, Group LM received 11 mg 0.5% levobupivacaine + 100 pg morphine and Group LFM received 11 mg 0.5 % levobupivacaine + 5 µg fentanyl + 50 µg morphine intrathecally. Results: Haemodynamies were affected much more in groups which included fentanyl and sensorial block level raised up faster (p<0.05). In groups where morphine was added sensorial block level increased slowly, time to start surgery get longer and in addition sensorial and motor block ceased later (p<0.05). Postoperative analgesia quality was better in morphine added groups (p<0.05). Levobupivacaine use by itself increased intraoperative nausea incidence whereas morphine addition increased postoperative itching (p