ABO blood groups and Rh factor are risk factors for Epithelial Ovarian Cancer?

WOS: 000495991100001Objective(s): The initial aim of this study is to research the allocation of blood types ABO and Rh factor antigens in patients with epithelial ovarian cancer (EOC). Design: Retrospective Setting: University Hospital (Tertiary center) Subjects: From the records at Zonguldak Bulent Ecevit University Faculty of Medicine Hospital in the period January 2010- June 2018, data on 100 EOC patients were obtained concerning blood groups ABO and Rh factor in 90 women. Intervention(s): The control group was constituted from the Zonguldak Bulent Ecevit University Faculty of Medicine Hospital Blood Transfusion Center and included 17065 females, to make reliable comparison, same region-same gender. Main Outcome Measure(s): Blood types ABO and Rh factors, patients having EOC. Result(s): Data on 90 women with EOC and recorded blood types ABO and Rh factors were taken for retrospective analysis. Although, blood type O was seemingly related with higher risk of EOC, this difference was not statistically significant. Also, blood type B was seemingly allocated with low risk of EOC, albeit this difference was not statistically significant. Condusion(s): Most previous studies have reported increased cancer of the ovaries associated with the A blood type compared to the O group. Contrary to our data, Zhang et al found that, blood type O is allocated with lower risk of cancer of the ovaries. Our studies results show possible allocation between the O blood type and higher risk of EOC B blood type and decreased probability EOC