25th Congress of the European Society of Biomechanics, VIENNE, AUTRICHE, 07-/07/2019 - 10/07/2019The difficulty to predict human cortical bone fragility is partly due to its complex multiscale architecture1. In particular, osteons, considered as bone structural units arise through the remodeling process that occurs at the canals surface, and are assumed to play a major role in bone mechanical properties2. If 2D data can be found in the literature, there is, however, still few 3D quantitative data regarding bone osteonal systems3. This lack of data can be explained by the difficulty to distinguish the osteon from the interstitial tissue using standard 3D imaging techniques. However, due to its sensitivity, synchrotron radiation micro-compute...