Yeast artificial chromosomes (YACs) permit the cloning of large tracts of human DNA. A YAC containing the human glucose-6-phosphate dehydrogenase gene is shown to encode active enzyme, supporting the inference that the YAC conserves the structure of the genomic DNA
Linear mammalian artificial chromosomes (MACs) will require functional teiomeres, a centromere and t...
AbstractA simple method for molecular cloning of fragments of more than one hundred kilobase pairs o...
Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic an...
The sequence of 20,114 bp of DNA including the human glucose-6-phosphate dehydrogenase (G6PD) gene w...
Yeast artificial chromosomes (YACs) have been applied to clone the entire class II region of the hum...
A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (...
Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragme...
The gene responsible for Huntington disease has been localized to a 2.5 million base pair (Mb) regio...
Three yeast artificial chromosome (YAC) libraries were constructed using two human cell lines and th...
Yeast artificial chromosomes (YACs; 1) are rapidly becoming the major cloning system to study eukary...
We describe the construction and characterization of a human X-chromosome-specific yeast artificial ...
An important goal of the Human Genome Project is the physical mapping of the human genome. This the...
Yeast artificial chromosomes (YACs) from the CEPH MegaYAC library (Paris, France) ranging in size fr...
Yeast artificial chromosomes (YACs) have recently provided a potential route to long-range coverage ...
We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human b...
Linear mammalian artificial chromosomes (MACs) will require functional teiomeres, a centromere and t...
AbstractA simple method for molecular cloning of fragments of more than one hundred kilobase pairs o...
Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic an...
The sequence of 20,114 bp of DNA including the human glucose-6-phosphate dehydrogenase (G6PD) gene w...
Yeast artificial chromosomes (YACs) have been applied to clone the entire class II region of the hum...
A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (...
Yeast artificial chromosomes (YACs) have become essential research tools as they enable large fragme...
The gene responsible for Huntington disease has been localized to a 2.5 million base pair (Mb) regio...
Three yeast artificial chromosome (YAC) libraries were constructed using two human cell lines and th...
Yeast artificial chromosomes (YACs; 1) are rapidly becoming the major cloning system to study eukary...
We describe the construction and characterization of a human X-chromosome-specific yeast artificial ...
An important goal of the Human Genome Project is the physical mapping of the human genome. This the...
Yeast artificial chromosomes (YACs) from the CEPH MegaYAC library (Paris, France) ranging in size fr...
Yeast artificial chromosomes (YACs) have recently provided a potential route to long-range coverage ...
We demonstrate that transfer of a yeast artificial chromosome (YAC) containing 230 kb of the human b...
Linear mammalian artificial chromosomes (MACs) will require functional teiomeres, a centromere and t...
AbstractA simple method for molecular cloning of fragments of more than one hundred kilobase pairs o...
Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic an...
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