Single‐stranded DNA‐binding proteins (SSBs) are required for all known DNA metabolic events such as DNA replication, recombination and repair. While a wealth of structural and functional data is available on the essential human SSB, hSSB1 (NABP2/OBFC2B), the close homolog hSSB2 (NABP1/OBFC2A) remains relatively uncharacterized. Both SSBs possess a well‐structured OB (oligonucleotide/oligosaccharide‐binding) domain that is able to recognize single‐stranded DNA (ssDNA) followed by a flexible carboxyl‐tail implicated in the interaction with other proteins. Despite the high sequence similarity of the OB domain, several recent studies have revealed distinct functional differences between hSSB1 and hSSB2. In this study, we show that hSSB2 is able...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Canonical single-stranded DNA binding proteins (SSBs) from the Oligosaccharide/Oligonucleotide Bindi...
Abstract Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, e...
Single-stranded DNA-binding proteins (SSBs) are required for all known DNA metabolic events such as ...
Single-stranded DNA-binding proteins (SSBs) are required for all known DNA metabolic events such as ...
Single stranded DNA-binding proteins (SSBs) are essential for the maintenance of genome integrity an...
Single-stranded DNA-binding proteins (SSBs) are highly important in DNA metabolism and play an essen...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding (SSB) proteins are essential to protect singe-stranded DNA (ssDNA) that ...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Canonical single-stranded DNA binding proteins (SSBs) from the Oligosaccharide/Oligonucleotide Bindi...
Abstract Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, e...
Single-stranded DNA-binding proteins (SSBs) are required for all known DNA metabolic events such as ...
Single-stranded DNA-binding proteins (SSBs) are required for all known DNA metabolic events such as ...
Single stranded DNA-binding proteins (SSBs) are essential for the maintenance of genome integrity an...
Single-stranded DNA-binding proteins (SSBs) are highly important in DNA metabolism and play an essen...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding proteins (SSBs) play an important role in DNA processing events such as ...
Single-stranded DNA binding (SSB) proteins are essential to protect singe-stranded DNA (ssDNA) that ...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic...
Canonical single-stranded DNA binding proteins (SSBs) from the Oligosaccharide/Oligonucleotide Bindi...
Abstract Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, e...