Sesquizygotic multiple pregnancy is an exceptional intermediate between monozygotic and dizygotic twinning. We report a monochorionic twin pregnancy with fetal sex discordance. Genotyping of amniotic fluid from each sac showed that the twins were maternally identical but chimerically shared 78% of their paternal genome, which makes them genetically in between monozygotic and dizygotic; they are sesquizygotic. We observed no evidence of sesquizygosis in 968 dizygotic twin pairs whom we screened by means of pangenome single-nucleotide polymorphism genotyping. Data from published repositories also show that sesquizygosis is a rare event. Detailed genotyping implicates chimerism arising at the juncture of zygotic division, termed heterogonesis,...
Objective: To prove monozygocity of human twin blastocysts derived from embryo splitting at the clea...
Dramatic genome dynamics, such as chromosome instability, contribute to the remarkable genomic heter...
DO MONOZYGOTIC TWINS HAVE IDENTICAL GENOTYPES? Recent observation of the fertilization process and ...
Traditionally, it is understood that dizygotic (DZ) twins always have a dichorionic placenta. Howeve...
Traditionally, monochorionic twins have been considered to be monozygous. This concept is founded up...
Common knowledge of over a century has it that monozygotic and dizygotic twinning events occur by un...
International audiencePreimplantation genetic testing (PGT) is widely used to select unaffected embr...
International audienceWe report twins for whom ultrasound examinations revealed a Turner syndrome in...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
The tendency to conceive spontaneous dizygotic (DZ) twins is a complex trait with important contribu...
Twin birth rates have increased markedly in developed countries since the 1970s for two primary reas...
Traditionally twins are classified as dizygous or fraternal and monozygous or identical (Hall Twinni...
We report a very rare case of monochorionic dizygotic twins conceived spontaneously. The fetuses wer...
Objective: To prove monozygocity of human twin blastocysts derived from embryo splitting at the clea...
Dramatic genome dynamics, such as chromosome instability, contribute to the remarkable genomic heter...
DO MONOZYGOTIC TWINS HAVE IDENTICAL GENOTYPES? Recent observation of the fertilization process and ...
Traditionally, it is understood that dizygotic (DZ) twins always have a dichorionic placenta. Howeve...
Traditionally, monochorionic twins have been considered to be monozygous. This concept is founded up...
Common knowledge of over a century has it that monozygotic and dizygotic twinning events occur by un...
International audiencePreimplantation genetic testing (PGT) is widely used to select unaffected embr...
International audienceWe report twins for whom ultrasound examinations revealed a Turner syndrome in...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
Prenatal diagnosis of simultaneous occurrence of chimerism and autosomal mosaicism is extremely rare...
The tendency to conceive spontaneous dizygotic (DZ) twins is a complex trait with important contribu...
Twin birth rates have increased markedly in developed countries since the 1970s for two primary reas...
Traditionally twins are classified as dizygous or fraternal and monozygous or identical (Hall Twinni...
We report a very rare case of monochorionic dizygotic twins conceived spontaneously. The fetuses wer...
Objective: To prove monozygocity of human twin blastocysts derived from embryo splitting at the clea...
Dramatic genome dynamics, such as chromosome instability, contribute to the remarkable genomic heter...
DO MONOZYGOTIC TWINS HAVE IDENTICAL GENOTYPES? Recent observation of the fertilization process and ...