Bioinformatics: From computational analysis through to integrated systems

The advent of large-scale genomic sequencing has resulted in masses of molecular sequences for a diverse range of organisms. There is a wealth of understanding to be gained from assimilating information by conducting extensive comparative genomic analysis. This information assists us in making reasoned interpretation on biological processes, evolutionary mechanisms as well as genomic and gene structure and characterization. More recently, the areas of functional genomics, transcriptomics, including the numerous international consortia for full-length cDNA projects, metabolomics, proteomics and structural biology are providing complementary data sources that provide further portals that assist in our understanding of the structure, function and evolution of genes and organisms from genome to phenome..