Cartridge Methods for Oligonucleotide Purification

Protocols are given for purification of oligonucleotides by dimethoxytrityl‐sensitive and affinity desalting methods. The protocols are applicable for many of the convenient disposable products available for rapid oligonucleotide purification, clean‐up by selective adsorption, and elution on solid‐phase media. Many of these products are prepackaged, single‐use cartridges or columns filled with affinity or size‐exclusion media.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152627/1/cpnc1007.pd