Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated Naþ channels. In doing so, they inhibit action potentials in nociceptive fibres and so block the transmission of pain impulses. This article describes nerve anatomy and physiology, the molecular site of action of local anaesthetics, and their pharmacology
The action potential (AP) conduction in nerve fibers plays a crucial role in transmitting nociceptiv...
Local anesthetic agents depress the excitability of nerve and skeletal muscle (Toman, 1952; Shanes, ...
Copyright © 2014 Yuhei Uemura et al. This is an open access article distributed under the Creative C...
Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated N...
Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. ...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
Localanesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it...
Local anesthetics inhibit the ion channel activity of nicotinic acetylcholine receptors in a noncomp...
In this thesis I try to clarify some molecular mechanisms of local anaesthetic action on ion channel...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
Transient receptor potential subfamily V, member 1 (TRPV1) channels are important integrators of nox...
Na channels are the source of excitatory currents for the nervous system and muscle. They are the ta...
In conclusion, it is possible to compile a list of salient features which are obviously important, ...
Background and Purpose: Pain is an unpleasant warning sensation of imminent damage of the tissue or ...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
The action potential (AP) conduction in nerve fibers plays a crucial role in transmitting nociceptiv...
Local anesthetic agents depress the excitability of nerve and skeletal muscle (Toman, 1952; Shanes, ...
Copyright © 2014 Yuhei Uemura et al. This is an open access article distributed under the Creative C...
Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated N...
Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. ...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
Localanesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it...
Local anesthetics inhibit the ion channel activity of nicotinic acetylcholine receptors in a noncomp...
In this thesis I try to clarify some molecular mechanisms of local anaesthetic action on ion channel...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
Transient receptor potential subfamily V, member 1 (TRPV1) channels are important integrators of nox...
Na channels are the source of excitatory currents for the nervous system and muscle. They are the ta...
In conclusion, it is possible to compile a list of salient features which are obviously important, ...
Background and Purpose: Pain is an unpleasant warning sensation of imminent damage of the tissue or ...
Many theories about the mechanism of action of local anesthetics (LA) are described in the literatur...
The action potential (AP) conduction in nerve fibers plays a crucial role in transmitting nociceptiv...
Local anesthetic agents depress the excitability of nerve and skeletal muscle (Toman, 1952; Shanes, ...
Copyright © 2014 Yuhei Uemura et al. This is an open access article distributed under the Creative C...
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