1. Antibodies have been raised against the Neurospora crassa arom complex, which is a pentafunctional enzyme that catalyses steps 2 to 6 in the shikimate pathway, and against the monofunctional enzymes from Escherichia coli, which catalyse the same reactions. In the case of the E. coli enzymes, antibodies were raised against both native and denatured proteins
The arom pentafunctional enzyme found in fungi catalyses five consecutive reactions of the shikimate...
A major part of this thesis involved using electrospray mass spectrometry to monitor the chemical mo...
<p>Shikimic acid (SA) pathway is the common route used by bacteria, plants, fungi, algae, and certai...
1. Antibodies have been raised against the Neurospora crassa arom complex, which is a pentafunctiona...
Aromatic compounds are synthesized via the shikimate pathway. The first activity, DAHP synthase, has...
Aromatic compounds are synthesised via the shikimate pathway. The fungal pentafunctional arom enzyme...
Aromatic compounds are made via the shikimate pathway. The N. crassa pentafunctional arom enzyme has...
The work in this thesis has been performed as part of an investigation into the upregulation of flux...
Background: The functional and structural characterisation of enzymes that belong to microbial metab...
Shikimate dehydrogenase (SKDH) catalyses the fourth step of the biosynthetic shikimate pathway, the ...
The shikimate pathway links carbohydrate metabolism to biosynthesis of the aromatic amino acids in p...
An improved method of purifying the arom complex from N. crassa has been devised. This procedure tak...
Practical conditions were developed for growing Neurospora crassa on a scale from which substantial ...
The shikimate dehydrogenase (SDH) family consists of at least five structurally related, but functio...
Bacteria, plants, fungi, and apicomplexan parasites require the functionality of the shikimate pathw...
The arom pentafunctional enzyme found in fungi catalyses five consecutive reactions of the shikimate...
A major part of this thesis involved using electrospray mass spectrometry to monitor the chemical mo...
<p>Shikimic acid (SA) pathway is the common route used by bacteria, plants, fungi, algae, and certai...
1. Antibodies have been raised against the Neurospora crassa arom complex, which is a pentafunctiona...
Aromatic compounds are synthesized via the shikimate pathway. The first activity, DAHP synthase, has...
Aromatic compounds are synthesised via the shikimate pathway. The fungal pentafunctional arom enzyme...
Aromatic compounds are made via the shikimate pathway. The N. crassa pentafunctional arom enzyme has...
The work in this thesis has been performed as part of an investigation into the upregulation of flux...
Background: The functional and structural characterisation of enzymes that belong to microbial metab...
Shikimate dehydrogenase (SKDH) catalyses the fourth step of the biosynthetic shikimate pathway, the ...
The shikimate pathway links carbohydrate metabolism to biosynthesis of the aromatic amino acids in p...
An improved method of purifying the arom complex from N. crassa has been devised. This procedure tak...
Practical conditions were developed for growing Neurospora crassa on a scale from which substantial ...
The shikimate dehydrogenase (SDH) family consists of at least five structurally related, but functio...
Bacteria, plants, fungi, and apicomplexan parasites require the functionality of the shikimate pathw...
The arom pentafunctional enzyme found in fungi catalyses five consecutive reactions of the shikimate...
A major part of this thesis involved using electrospray mass spectrometry to monitor the chemical mo...
<p>Shikimic acid (SA) pathway is the common route used by bacteria, plants, fungi, algae, and certai...