Fetal androgen exposure is a determinant of adult male metabolic health

In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis.

Kanellopoulos-Langevin, Colette
Connolly, Fiona
Rae, Mick T
Boswell, Lyndsey
McNeilly, Alan S.
Duncan, W. Colin

July 2015

Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-...

Contributions of androgen and estrogen to fetal programming of ovarian dysfunction

Abbott, David H
Padmanabhan, Vasantha
Dumesic, Daniel A

August 2015

Abstract In female mammals, including humans, deviations from normal androgenic or est...

Characterisation of the androgen dependent phenotype

Rodie, Martina Elizabeth

January 2017

The effects of androgens reach far and wide and can be physiological as well as pathological. They a...

Fetal androgen exposure is a determinant of adult male metabolic health

Siemienowicz, Katarzyna
Filis, Panagiotis
Shaw, Sophie
Douglas, Alex
Thomas, Jennifer
Mulroy, Sally
Howie, Forbes
Fowler , Paul A
Duncan, W. Colin
Rae, Mick T

December 2019

This work was funded by Medical Research Council (MRC) project grant (G0901807) to WCD and MTR, and ...

Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life

Siemienowicz, Katarzyna
Filis, Panagiotis
Shaw, Sophie
Douglas, Alex
Thomas, Jennifer
Howie, Forbes
Fowler, Paul
Duncan, Colin
Rae, Mick

January 2019

Introduction: Adult male offspring of women with PCOS have increased dyslipidaemia, characterised by...

Prenatal exposure to androgens as a factor of fetal programming

Recabarren, Sergio E.
Sir Petermann, Lidia
Maliqueo Yevilao, Manuel
Lobos, Alejandro
Rojas García, Pedro

January 2006

Both epidemiological and clinical evidence suggest a relationship between the prenatal environment ...

Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of “PCOS Males”

Siemienowicz, Katarzyna J.
Filis, Panagiotis
Thomas, Jennifer
Fowler, Paul A.
Duncan, W. Colin
Rae, Mick T.

January 2022

First-degree male relatives of polycystic ovary syndrome (PCOS) sufferers can develop metabolic abno...

Investigating the sex-specific legacy of excessive fetal androgen exposure on immune function and hepatic health

Thomas, Jennifer Lyndsey

Background: It is well established that there are sex-specific differences in immune competence, wit...

Reproductive and metabolic programming by exogenous steroids

Connolly, Fiona

July 2014

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder encompassing reproductive and metaboli...

Elucidating the effect of prenatal androgen excess on male reproductive function

Holland, Sarah Louise

June 2019

The in utero nutritional and hormonal environment is critical in shaping the developing male and fem...

Fetal programming by androgen excess impairs liver lipid content and PPARg expression in adult rats

Silva, Aimé Florencia
Abruzzese, Giselle Adriana
Ferrer, María José
Heber, María Florencia
Ferreira, Silvana Rocio
Cerrone, Gloria Edith
Motta, Alicia Beatriz

June 2021

It is known that prenatal hyperandrogenization induces alterations since early stages of life, contr...

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)

Franks, Stephen
Rae, Mick T
Grace, Cathal
Hogg, Kirsten
Wilson, Lisa Marie
McHaffie, Sophie L
Ramaswamy, Seshadri
MacCallum, Janis
Connolly, Fiona
McNeilly, Alan S
Duncan, Colin

February 2013

Using an ovine model of polycystic ovary syndrome (PCOS), (pregnant ewes injected with testosterone ...

Prenatal exposure to androgens as a factor of fetal programming La exposición prenatal a andrógenos como factor de reprogramación fetal

Recabarren, Sergio E.
Sir Petermann, Teresa
Maliqueo Yevilao, Manuel
Lobos, Alejandro
Rojas García, Pedro

January 2006

Both epidemiological and clinical evidence suggest a relationship between the prenatal environment a...

In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis.

Kanellopoulos-Langevin, Colette
Connolly, Fiona
Rae, Mick T
Boswell, Lyndsey
McNeilly, Alan S.
Duncan, W. Colin

July 2015

Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-...

Contributions of androgen and estrogen to fetal programming of ovarian dysfunction

Abbott, David H
Padmanabhan, Vasantha
Dumesic, Daniel A

August 2015

Abstract In female mammals, including humans, deviations from normal androgenic or est...

Characterisation of the androgen dependent phenotype

Rodie, Martina Elizabeth

January 2017

The effects of androgens reach far and wide and can be physiological as well as pathological. They a...

Fetal androgen exposure is a determinant of adult male metabolic health

Siemienowicz, Katarzyna
Filis, Panagiotis
Shaw, Sophie
Douglas, Alex
Thomas, Jennifer
Mulroy, Sally
Howie, Forbes
Fowler , Paul A
Duncan, W. Colin
Rae, Mick T

December 2019

This work was funded by Medical Research Council (MRC) project grant (G0901807) to WCD and MTR, and ...

Dyslipidaemia and altered hepatic function in males - consequences of androgen excess in fetal life

Siemienowicz, Katarzyna
Filis, Panagiotis
Shaw, Sophie
Douglas, Alex
Thomas, Jennifer
Howie, Forbes
Fowler, Paul
Duncan, Colin
Rae, Mick

January 2019

Introduction: Adult male offspring of women with PCOS have increased dyslipidaemia, characterised by...

Prenatal exposure to androgens as a factor of fetal programming

Recabarren, Sergio E.
Sir Petermann, Lidia
Maliqueo Yevilao, Manuel
Lobos, Alejandro
Rojas García, Pedro

January 2006

Both epidemiological and clinical evidence suggest a relationship between the prenatal environment ...

Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of “PCOS Males”

Siemienowicz, Katarzyna J.
Filis, Panagiotis
Thomas, Jennifer
Fowler, Paul A.
Duncan, W. Colin
Rae, Mick T.

January 2022

First-degree male relatives of polycystic ovary syndrome (PCOS) sufferers can develop metabolic abno...

Investigating the sex-specific legacy of excessive fetal androgen exposure on immune function and hepatic health

Thomas, Jennifer Lyndsey

Background: It is well established that there are sex-specific differences in immune competence, wit...

Reproductive and metabolic programming by exogenous steroids

Connolly, Fiona

July 2014

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder encompassing reproductive and metaboli...

Elucidating the effect of prenatal androgen excess on male reproductive function

Holland, Sarah Louise

June 2019

The in utero nutritional and hormonal environment is critical in shaping the developing male and fem...

Fetal programming by androgen excess impairs liver lipid content and PPARg expression in adult rats

Silva, Aimé Florencia
Abruzzese, Giselle Adriana
Ferrer, María José
Heber, María Florencia
Ferreira, Silvana Rocio
Cerrone, Gloria Edith
Motta, Alicia Beatriz

June 2021

It is known that prenatal hyperandrogenization induces alterations since early stages of life, contr...

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)

Franks, Stephen
Rae, Mick T
Grace, Cathal
Hogg, Kirsten
Wilson, Lisa Marie
McHaffie, Sophie L
Ramaswamy, Seshadri
MacCallum, Janis
Connolly, Fiona
McNeilly, Alan S
Duncan, Colin

February 2013

Using an ovine model of polycystic ovary syndrome (PCOS), (pregnant ewes injected with testosterone ...

Prenatal exposure to androgens as a factor of fetal programming La exposición prenatal a andrógenos como factor de reprogramación fetal

Recabarren, Sergio E.
Sir Petermann, Teresa
Maliqueo Yevilao, Manuel
Lobos, Alejandro
Rojas García, Pedro

January 2006

Both epidemiological and clinical evidence suggest a relationship between the prenatal environment a...

In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis.

Kanellopoulos-Langevin, Colette
Connolly, Fiona
Rae, Mick T
Boswell, Lyndsey
McNeilly, Alan S.
Duncan, W. Colin

July 2015

Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-...

Contributions of androgen and estrogen to fetal programming of ovarian dysfunction

Abbott, David H
Padmanabhan, Vasantha
Dumesic, Daniel A

August 2015

Abstract In female mammals, including humans, deviations from normal androgenic or est...

Characterisation of the androgen dependent phenotype

Rodie, Martina Elizabeth

January 2017

The effects of androgens reach far and wide and can be physiological as well as pathological. They a...

Fetal androgen exposure is a determinant of adult male metabolic health

Abstract

Extracted data

Fetal androgen exposure is a determinant of adult male metabolic health

Abstract

Extracted data

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