ANTIMICROBIAL SENSITIVITY OF NEISSERIA GONORRHOEA IN GONDAR, ETHIOPIA

Objeciives: To determine the antimicrobial wsceptibility pattern of N ~ i s s e ~ gonorrheaeand to obtain epidemiological information on resistance of Neisseriu gonorrheae in Gondartown.Design: A cross sectional study.Setting: Gondar Health Centre.Subjects: One hundred and seventy eight male paticnts preserhkd with urethral dischargeand who volunteered to participate in the study were included.Results: A total of 142 strains of N. gonorrhoeae were isolated from I68 cultures received. Thesensitivity of gonococcal isolates ranges from 98.6% to chloramphetiicvl tu 7.7% tocotrimoxazole. Multiple drag resistance was reported in 87.5% of isolates and only fourisolates were sensitive to all antibiotics. One strain of N. gonorrheae was resistant to as manyas eight antibiotics (lrtrauycline, penicillin, ampicillin, ksnamicin, methicilin. uarbcnicillin,crltrirnoxazole and ceftriaxone). More than eighty five per cent of the isotated strains werepenicillinase-producing Neisseria gunorrltoene (PPN G).Conclusion: Gonococcal resistance is a significant public health problem in Gondar regionand the drugs recommended for treatment of gonococcal cases by the national sexuallytransmitted diwdsm (STDs) control programme need to be revised