ANTIBIOGRAM AND SUSCEPTIBILITY OF KLEBSIELLA SPP ISOLATED FROM DIFFERENT CLINICAL SPECIMENS IN HEALTH CARE CENTERS IN ETSAKO WEST LOCAL GOVERNMENT AREA OF EDO STATE, NIGERIA

Arising multidrug resistance to available antibiotics is a problem of deep scientific and research concern. One organism with increasing antibiotics resistance is Klebsiella spp. that had cause several outbreaks in different locations. This study was undertaken to investigate the antibiogram and susceptibility of Klebsiella spp. isolated from clinical samples in health care centers. The study was conducted in Auchi Township in Etsako West Local Government Area, Edo State, Nigeria. Following standard procedures samples were collected and Klebsiella spp. identified using standard microbiology techniques. Antibiotic susceptibility testing was carried out using standard methods. 109 samples were collected and comprised urine (44), wound (20), high vagina swabs (17), urethral (3), sputum (9), semen (6), stool (5), endo-cervical swab (2), throat (1) and ear (1). 10 (9.17%) samples were positive to Klebsiella organism with urine consisting 50.0% and 10.0% each from sputum, stool, wound, ear and high vaginal swabs. Klebsiella isolates were completely resistance to penicillin, Amoxiclav and Chloramphenic. Amoxicillin, Floxapen, Metronidazole, Ampicillin, Cotrimoxazole, Nalidixic acid, Streptomycin, Tetracycline, Cephalexin, Genticin, Tobramycin, Nitrofurantoin, Ciprofloxacine and Cefuroxime have less than 50% potency. On the other hand, Ofloxacine, Cefotaxime, Ampisulbactam and Perflacine were 50% and above susceptible. Klesiella spp. isolated from stool sample was more multi-drug resistance (87.75%) followed by those from wound (77.55%), sputum (73.47%), high vaginal swab (69.39%), urine (65.30%) and lastly ear sample (48.98). Based on our findings, Klebsiella spp. in the study area is multidrug-resistance thus suggesting antibiotic analysis prior to treatment