Interventions for reducing benzodiazepine use in older people: Meta-analysis of randomised controlled trials

Background The use of benzodiazepines has been advised against in older people, but prevalence rates remain high. Aims To review the evidence for interventions aimed at reducing benzodiazepine use in older people. Method We conducted a systematic review, assessment of risk of bias and meta-analyses of randomised controlled trials of benzodiazepine withdrawal and prescribing interventions. Results Ten withdrawal and eight prescribing studies met the inclusion criteria. At post-intervention, significantly higher odds of not using benzodiazepines were found with supervised withdrawal with psychotherapy (odds ratio (OR) = 5.06, 95% CI 2.68–9.57, P